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| Hengqin Life WTA Elite Trophy | ||
| Surface: Hard | Date: Oct. 22 - Oct. 27 | Seed: 9 |
| Round | Opponent | W / L | Result |
| Round Robin | Aryna Sabalenka | Loss | 3-6, 4-6 2-6, 6-3, 1-6 |
| Round Robin | Elise Mertens | Loss | 3-6, 4-6 2-6, 6-3, 1-6 |
| VTB Kremlin Cup | ||
| Surface: Hard | Date: Oct. 14 - Oct. 20 | Seed: 7 |
| Round | Opponent | W / L | Result |
| First Round | Anastasia Pavlyuchenkova | Loss | 7-5, 1-6, 3-6 |
| US Open | ||
| Surface: Hard | Date: Aug. 26 - Sep. 8 | Seed: 30 |
| Round | Opponent | W / L | Result |
| First Round | Camila Giorgi | Win | 6-1, 6-0 |
| Second Round | Shuai Peng | Win | 6-7 (5-7), 6-4, 6-2 |
| Third Round | Ashleigh Barty | Loss | 5-7, 3-6 |
| Western & Southern Womens Open | ||
| Surface: Hard | Date: Aug. 11 - Aug. 18 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Camila Giorgi | Win | 6-3, 6-0 |
| Second Round | Petra Kvitova | Win | 6-4, 2-6, 6-3 |
| Third Round | Aryna Sabalenka | Win | 6-7 (4-7), 6-4, 6-4 |
| Quarterfinals | Ashleigh Barty | Loss | 7-5, 2-6, 0-6 |
| Rogers Cup presented by National Bank | ||
| Surface: Hard | Date: Aug. 5 - Aug. 11 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Alison Riske | Loss | 6-4, 2-6, 6-7 (7-9) |
| Mubadala Silicon Valley Classic | ||
| Surface: Hard | Date: Jul. 29 - Aug. 4 | Seed: 7 |
| Round | Opponent | W / L | Result |
| First Round | Ekaterina Alexandrova | Win | 6-1, 6-4 |
| Second Round | Mayo Hibi | Win | 4-6, 6-4, 6-2 |
| Quarterfinals | Elina Svitolina | Win | 1-6, 7-6 (7-3), 6-3 |
| Semifinals | Saisai Zheng | Loss | 6-7 (5-7), 2-6 |
| Wimbledon | ||
| Surface: Grass | Date: Jul. 1 - Jul. 14 | Seed: 31 |
| Round | Opponent | W / L | Result |
| First Round | Bernarda Pera | Win | 7-6 (7-4), 6-3 |
| Second Round | Marie Bouzkova | Win | 6-4, 6-1 |
| Third Round | Elina Svitolina | Loss | 3-6, 7-6 (7-1), 2-6 |
| Nature Valley International | ||
| Surface: Grass | Date: Jun. 23 - Jun. 29 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Jessica Pegula | Win | 6-2, 6-1 |
| Second Round | Johanna Konta | Loss | 4-6, 6-7 (4-7) |
| Nature Valley Classic | ||
| Surface: Grass | Date: Jun. 17 - Jun. 23 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Naomi Osaka | Loss | 1-6, 6-4, 3-6 |
| Nature Valley Open | ||
| Surface: Grass | Date: Jun. 10 - Jun. 16 | Seed: 4 |
| Round | Opponent | W / L | Result |
| First Round | Heather Watson | Win | 6-4, 6-3 |
| Second Round | Ivana Jorovic | Win | 6-2, 6-4 |
| Quarterfinals | Jennifer Brady | Loss | 5-7, 3-6 |
| Roland Garros | ||
| Surface: Red Clay | Date: May 26 - Jun. 9 | Seed: 29 |
| Round | Opponent | W / L | Result |
| First Round | Anna Tatishvili | Win | 6-0, 6-1 |
| Second Round | Katerina Siniakova | Loss | 6-7 (5-7), 7-6 (10-8), 3-6 |
| Internazionali BNL d'Italia | ||
| Surface: Red Clay | Date: May 12 - May 19 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Anastasia Pavlyuchenkova | Win | 6-1, 7-5 |
| Second Round | Anett Kontaveit | Win | 6-3, 6-2 |
| Third Round | Petra Kvitova | Win | 7-5, 5-7, 4-0 Retired |
| Quarterfinals | Kristina Mladenovic | Win | 5-7, 6-3, 6-0 |
| Semifinals | Karolina Pliskova | Loss | 4-6, 4-6 |
| Mutua Madrid Open | ||
| Surface: Hard | Date: May 4 - May 12 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Carla Suarez Navarro | Loss | 3-6, 3-6 |
| Grand Prix De SAR La Princesse Lalla Meryem | ||
| Surface: Clay | Date: Apr. 29 - May 4 | Seed: 6 |
| Round | Opponent | W / L | Result |
| First Round | Olga Danilovic | Win | 6-0, 6-2 |
| Second Round | Isabella Shinikova | Win | 6-4, 6-4 |
| Quarterfinals | Elise Mertens | Win | 6-4, 7-6 (7-2) |
| Semifinals | Alison Van Uytvanck | Win | 6-4, 6-4 |
| Final | Johanna Konta | Win | 2-6, 6-4, 6-1 |
| TEB BNP Paribas Istanbul Cup | ||
| Surface: Clay | Date: Apr. 22 - Apr. 28 | Seed: 8 |
| Round | Opponent | W / L | Result |
| First Round | Veronika Kudermetova | Loss | 3-6, 4-6 |
| Volvo Car Open | ||
| Surface: Green Clay | Date: Apr. 1 - Apr. 7 | Seed: 15 |
| Round | Opponent | W / L | Result |
| First Round | Conny Perrin | Win | 7-5, 3-6, 6-1 |
| Second Round | Andrea Petkovic | Win | 6-3, 6-0 |
| Third Round | Kiki Bertens | Win | 7-6 (10-8), 6-3 |
| Quarterfinals | Caroline Wozniacki | Loss | 2-6, 2-6 |
| Miami Open presented by Itau | ||
| Surface: Hard | Date: Mar. 19 - Mar. 31 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Olga Danilovic | Win | 1-6, 6-3, 6-4 |
| Second Round | Petra Kvitova | Loss | 1-6, 4-6 |
| BNP Paribas Open | ||
| Surface: Hard | Date: Mar. 6 - Mar. 17 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Christina McHale | Loss | 5-7, 0-6 |
| Abierto Mexicano TELCEL presentado por HSBC | ||
| Surface: Hard | Date: Feb. 25 - Mar. 3 | Seed: 6 |
| Round | Opponent | W / L | Result |
| First Round | Monica Puig | Loss | 5-7, 6-4, 0-6 |
| St. Petersburg Ladies Trophy | ||
| Surface: Hard | Date: Jan. 28 - Feb. 3 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Julia Goerges | Loss | 2-6, 5-7 |
| Australian Open | ||
| Surface: Hard | Date: Jan. 14 - Jan. 27 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Jelena Ostapenko | Win | 6-1, 3-6, 6-2 |
| Second Round | Astra Sharma | Win | 6-1, 6-4 |
| Third Round | Ashleigh Barty | Loss | 5-7, 1-6 |
| Hobart International | ||
| Surface: Hard | Date: Jan. 7 - Jan. 12 | Seed: 4 |
| Round | Opponent | W / L | Result |
| First Round | Magda Linette | Loss | 6-3, 2-6, 4-6 |
