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| Hengqin Life WTA Elite Trophy | ||
| Surface: Hard | Date: Oct. 22 - Oct. 27 | Seed: 8 |
| Round | Opponent | W / L | Result |
| Round Robin | Kiki Bertens | Loss | 6-7 (5-7), 2-6 6-7 (6-8), 2-6 |
| Round Robin | Dayana Yastremska | Loss | 6-7 (5-7), 2-6 6-7 (6-8), 2-6 |
| VTB Kremlin Cup | ||
| Surface: Hard | Date: Oct. 14 - Oct. 20 | Seed: 4 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Karolina Muchova | Loss | 4-6, 2-6 |
| Upper Austria Ladies Linz | ||
| Surface: Hard | Date: Oct. 7 - Oct. 13 | Seed: 4 |
| Round | Opponent | W / L | Result |
| First Round | Polona Hercog | Win | 6-1, 6-1 |
| Second Round | Kristina Mladenovic | Loss | 6-3, 1-6, 2-6 |
| China Open | ||
| Surface: Hard | Date: Sep. 28 - Oct. 6 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Kiki Bertens | Loss | 6-3, 1-6, 6-7 (3-7) |
| Dongfeng Motor Wuhan Open | ||
| Surface: Hard | Date: Sep. 22 - Sep. 28 | Seed: 16 |
| Round | Opponent | W / L | Result |
| First Round | Ons Jabeur | Loss | 6-4, 3-6, 3-6 |
| Toray Pan Pacific Open | ||
| Surface: Decoturf | Date: Sep. 16 - Sep. 22 | Seed: 7 |
| Round | Opponent | W / L | Result |
| First Round | Caroline Garcia | Win | 7-5, 6-2 |
| Second Round | Misaki Doi | Loss | 6-7 (5-7), 3-6 |
| US Open | ||
| Surface: Hard | Date: Aug. 26 - Sep. 8 | Seed: 23 |
| Round | Opponent | W / L | Result |
| First Round | Richel Hogenkamp | Win | 7-6 (7-4), 6-3 |
| Second Round | Kaia Kanepi | Win | 7-5, 6-3 |
| Third Round | Yulia Putintseva | Win | 6-4, 6-1 |
| Fourth Round | Julia Goerges | Win | 6-7 (5-7), 7-5, 6-3 |
| Quarterfinals | Belinda Bencic | Loss | 6-7 (5-7), 3-6 |
| Western & Southern Womens Open | ||
| Surface: Hard | Date: Aug. 11 - Aug. 18 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Katerina Siniakova | Win | 6-4, 6-3 |
| Second Round | Victoria Azarenka | Win | 6-2, 7-5 |
| Third Round | Venus Williams | Loss | 6-2, 3-6, 3-6 |
| Rogers Cup presented by National Bank | ||
| Surface: Hard | Date: Aug. 5 - Aug. 11 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Madison Keys | Win | 3-6, 7-6 (7-5), 7-6 (7-5) |
| Second Round | Svetlana Kuznetsova | Loss | 6-7 (4-7), 3-6 |
| Mubadala Silicon Valley Classic | ||
| Surface: Hard | Date: Jul. 29 - Aug. 4 | Seed: 5 |
| Round | Opponent | W / L | Result |
| First Round | Misaki Doi | Win | 6-4, 3-6, 6-4 |
| Second Round | Victoria Azarenka | Win | 6-4, 6-3 |
| Quarterfinals | Kristie Ahn | Win | 7-5, 6-0 |
| Semifinals | Aryna Sabalenka | Loss | 4-6, 3-6 |
| Wimbledon | ||
| Surface: Grass | Date: Jul. 1 - Jul. 14 | Seed: 22 |
| Round | Opponent | W / L | Result |
| First Round | Alison Riske | Loss | 6-3, 3-6, 5-7 |
| Nature Valley Classic | ||
| Surface: Grass | Date: Jun. 17 - Jun. 23 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Ashleigh Barty | Loss | 3-6, 4-6 |
| Nature Valley Open | ||
| Surface: Grass | Date: Jun. 10 - Jun. 16 | Seed: 2 |
| Round | Opponent | W / L | Result |
| First Round | Dalila Jakupovic | Win | 6-2, 6-7 (5-7), 6-0 |
| Second Round | Chloe Paquet | Win | 6-1, 6-2 |
| Quarterfinals | Kristina Mladenovic | Win | 7-5, 6-4 |
| Semifinals | Tatjana Maria | Win | 5-7, 6-0, 6-0 |
| Final | Caroline Garcia | Loss | 6-2, 6-7 (4-7), 6-7 (4-7) |
| Roland Garros | ||
| Surface: Red Clay | Date: May 26 - Jun. 9 | Seed: 23 |
| Round | Opponent | W / L | Result |
| First Round | Liudmila Samsonova | Win | 6-2, 6-4 |
| Second Round | Rebecca Peterson | Win | 1-6, 6-1, 6-2 |
| Third Round | Belinda Bencic | Win | 6-4, 6-1 |
| Fourth Round | Johanna Konta | Loss | 2-6, 4-6 |
| Mutua Madrid Open | ||
| Surface: Hard | Date: May 4 - May 12 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Qiang Wang | Win | 7-5, 6-4 |
| Second Round | Kristyna Pliskova | Win | 6-4, 6-4 |
| Third Round | Petra Martic | Loss | 6-4, 3-6, 0-3 Retired |
| Porsche Tennis Grand Prix | ||
| Surface: Clay | Date: Apr. 22 - Apr. 28 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Giulia Gatto-Monticone | Win | 6-1, 7-5 |
| Second Round | Daria Kasatkina | Win | 6-1, 7-5 |
| Quarterfinals | Naomi Osaka | Loss | 3-6, 6-4, 6-7 (4-7) |
| Miami Open presented by Itau | ||
| Surface: Hard | Date: Mar. 19 - Mar. 31 | Seed: 26 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Sara Sorribes Tormo | Win | 6-3, 6-3 |
| Third Round | Petra Kvitova | Loss | 4-6, 6-3, 4-6 |
| BNP Paribas Open | ||
| Surface: Hard | Date: Mar. 6 - Mar. 17 | Seed: 28 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Ysaline Bonaventure | Loss | 6-1, 6-7 (5-7), 4-6 |
| Abierto Mexicano TELCEL presentado por HSBC | ||
| Surface: Hard | Date: Feb. 25 - Mar. 3 | Seed: 3 |
| Round | Opponent | W / L | Result |
| First Round | Misaki Doi | Win | 6-0, 6-3 |
| Second Round | Christina McHale | Win | 6-4, 7-5 |
| Quarterfinals | Johanna Konta | Win | 6-3, 7-5 |
| Semifinals | Yafan Wang | Loss | 6-2, 3-6, 1-6 |
| Dubai Duty Free Tennis Championships | ||
| Surface: Hard | Date: Feb. 17 - Feb. 23 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Ons Jabeur | Loss | 4-6, 6-7 (9-11) |
| St. Petersburg Ladies Trophy | ||
| Surface: Hard | Date: Jan. 28 - Feb. 3 | Seed: 8 |
| Round | Opponent | W / L | Result |
| First Round | Timea Bacsinszky | Win | 4-6, 6-1, 6-3 |
| Second Round | Veronika Kudermetova | Win | 6-4, 6-3 |
| Quarterfinals | Petra Kvitova | Win | 6-4, 6-1 |
| Semifinals | Vera Zvonareva | Win | 6-2, 6-2 |
| Final | Kiki Bertens | Loss | 6-7 (2-7), 4-6 |
| Australian Open | ||
| Surface: Hard | Date: Jan. 14 - Jan. 27 | Seed: 29 |
| Round | Opponent | W / L | Result |
| First Round | Kristina Mladenovic | Win | 6-2, 6-4 |
| Second Round | Kimberly Birrell | Loss | 4-6, 6-4, 1-6 |
| Brisbane International presented by Suncorp | ||
| Surface: Hard | Date: Dec. 31 - Jan. 6 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Magdalena Rybarikova | Win | 6-1, 6-2 |
| Second Round | Kiki Bertens | Win | 7-6 (7-5), 1-6, 7-5 |
| Quarterfinals | Aliaksandra Sasnovich | Win | 6-2, 6-0 |
| Semifinals | Karolina Pliskova | Loss | 3-6, 4-6 |
