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| Volvo Car Open | ||
| Surface: Green Clay | Date: Apr. 5 - Apr. 11 | Seed: 1 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Misaki Doi | Win | 6-2, 6-1 |
| Third Round | Shelby Rogers | Win | 7-6 (7-3), 4-6, 6-4 |
| Quarterfinals | Paula Badosa | Loss | 4-6, 3-6 |
| Miami Open presented by Itau | ||
| Surface: Hard | Date: Mar. 23 - Apr. 4 | Seed: 1 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Kristina Kucova | Win | 6-3, 4-6, 7-5 |
| Third Round | Jelena Ostapenko | Win | 6-3, 6-2 |
| Fourth Round | Victoria Azarenka | Win | 6-1, 1-6, 6-2 |
| Quarterfinals | Aryna Sabalenka | Win | 6-4, 6-7 (5-7), 6-3 |
| Semifinals | Elina Svitolina | Win | 6-3, 6-3 |
| Final | Bianca Andreescu | Win | 6-3, 4-0 Retired |
| Adelaide International | ||
| Surface: Hard | Date: Feb. 22 - Feb. 27 | Seed: 1 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Danielle Collins | Loss | 3-6, 4-6 |
| Australian Open | ||
| Surface: Hard | Date: Feb. 8 - Feb. 21 | Seed: 1 |
| Round | Opponent | W / L | Result |
| First Round | Danka Kovinic | Win | 6-0, 6-0 |
| Second Round | Daria Gavrilova | Win | 6-1, 7-6 (9-7) |
| Third Round | Ekaterina Alexandrova | Win | 6-2, 6-4 |
| Fourth Round | Shelby Rogers | Win | 6-3, 6-4 |
| Quarterfinals | Karolina Muchova | Loss | 6-1, 3-6, 2-6 |
| Yarra Valley Classic | ||
| Surface: Hard | Date: Jan. 31 - Feb. 6 | Seed: 1 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Ana Bogdan | Win | 6-3, 6-3 |
| Third Round | Marie Bouzkova | Win | 6-0, 4-6, 6-3 |
| Quarterfinals | Shelby Rogers | Win | 7-5, 2-6, 10-4 |
| Semifinals | Serena Williams | Win | Retired |
| Final | Garbine Muguruza | Win | 7-6 (7-3), 6-4 |
