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| China Open | ||
| Surface: Hard | Date: Sep. 29 - Oct. 7 | Seed: 16 |
| Round | Opponent | W / L | Result |
| First Round | Bye |
| Dongfeng Motor Wuhan Open | ||
| Surface: Hard | Date: Sep. 23 - Sep. 29 | Seed: 16 |
| Round | Opponent | W / L | Result |
| First Round | Johanna Konta | Win | 7-5, 6-4 |
| Second Round | Saisai Zheng | Win | 4-6, 6-1, 6-2 |
| Third Round | Angelique Kerber | Win | 7-5, 6-1 |
| Quarterfinals | Anastasia Pavlyuchenkova | Win | 6-2, 5-7, 6-4 |
| Semifinals | Aryna Sabalenka | Loss | 6-7 (2-7), 4-6 |
| Toray Pan Pacific Open | ||
| Surface: Hard | Date: Sep. 17 - Sep. 23 | Seed: 7 |
| Round | Opponent | W / L | Result |
| First Round | Coco Vandeweghe | Win | 4-6, 6-3, 7-5 |
| Second Round | Victoria Azarenka | Loss | 4-6, 2-6 |
| US Open | ||
| Surface: Hard | Date: Aug. 27 - Sep. 9 | Seed: 18 |
| Round | Opponent | W / L | Result |
| First Round | Ons Jabeur | Win | 6-1, 6-3 |
| Second Round | Lucie Safarova | Win | 7-5, 6-3 |
| Third Round | Karolina Muchova | Win | 6-3, 6-4 |
| Fourth Round | Karolina Pliskova | Loss | 4-6, 4-6 |
| Western & Southern Womens Open | ||
| Surface: Hard | Date: Aug. 12 - Aug. 19 | Seed: 16 |
| Round | Opponent | W / L | Result |
| First Round | Marketa Vondrousova | Win | 6-3, 7-5 |
| Second Round | Kaia Kanepi | Win | 7-5, 6-3 |
| Third Round | Simona Halep | Loss | 5-7, 4-6 |
| Coupe Rogers presentee par Banque Nationale | ||
| Surface: Hard | Date: Aug. 6 - Aug. 12 | Seed: 15 |
| Round | Opponent | W / L | Result |
| First Round | Irina-Camelia Begu | Win | 6-3, 1-6, 7-5 |
| Second Round | Alison Van Uytvanck | Win | 7-6 (9-7), 6-2 |
| Third Round | Alize Cornet | Win | 7-6 (7-3), 6-4 |
| Quarterfinals | Kiki Bertens | Win | 6-3, 6-1 |
| Semifinals | Simona Halep | Loss | 4-6, 1-6 |
| Wimbledon | ||
| Surface: Grass | Date: Jul. 2 - Jul. 15 | Seed: 17 |
| Round | Opponent | W / L | Result |
| First Round | Stefanie Voegele | Win | 7-5, 6-3 |
| Second Round | Eugenie Bouchard | Win | 6-4, 7-5 |
| Third Round | Daria Kasatkina | Loss | 5-7, 3-6 |
| Nature Valley International | ||
| Surface: Grass | Date: Jun. 24 - Jun. 30 | Seed: 8 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Kristina Mladenovic | Win | 6-3, 6-2 |
| Third Round | Su-Wei Hsieh | Win | 6-0, 6-4 |
| Quarterfinals | Caroline Wozniacki | Loss | 4-6, 3-6 |
| Nature Valley Classic | ||
| Surface: Grass | Date: Jun. 18 - Jun. 24 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Oceane Dodin | Win | 6-4, 6-3 |
| Second Round | Julia Goerges | Loss | 6-7 (6-8), 3-6 |
| Nature Valley Open | ||
| Surface: Grass | Date: Jun. 11 - Jun. 17 | Seed: 1 |
| Round | Opponent | W / L | Result |
| First Round | Stefanie Voegele | Win | 6-3, 6-3 |
| Second Round | Ying-Ying Duan | Win | 6-3, 6-2 |
| Quarterfinals | Katie Boulter | Win | 6-0, 6-2 |
| Semifinals | Naomi Osaka | Win | 6-3, 6-4 |
| Final | Johanna Konta | Win | 6-3, 3-6, 6-4 |
| Roland Garros | ||
| Surface: Red Clay | Date: May 27 - Jun. 10 | Seed: 17 |
| Round | Opponent | W / L | Result |
| First Round | Natalia Vikhlyantseva | Win | 6-3, 6-1 |
| Second Round | Serena Williams | Loss | 6-3, 3-6, 4-6 |
| Internationaux de Strasbourg | ||
| Surface: Clay | Date: May 20 - May 26 | Seed: 1 |
| Round | Opponent | W / L | Result |
| First Round | Luksika Kumkhum | Win | 6-4, 6-4 |
| Second Round | Pauline Parmentier | Win | 6-1, 6-4 |
| Quarterfinals | Qiang Wang | Win | 7-5, 6-4 |
| Semifinals | Anastasia Pavlyuchenkova | Loss | 4-6, 0-1 Retired |
| Internazionali BNL d'Italia | ||
| Surface: Red Clay | Date: May 13 - May 20 | Seed: 16 |
| Round | Opponent | W / L | Result |
| First Round | Maria Sharapova | Loss | 5-7, 6-3, 2-6 |
| Mutua Madrid Open | ||
| Surface: Red Clay | Date: May 5 - May 13 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Sara Errani | Win | 6-1, 6-4 |
| Second Round | Caroline Wozniacki | Loss | 2-6, 6-4, 4-6 |
| Volvo Car Open | ||
| Surface: Green Clay | Date: Apr. 2 - Apr. 8 | Seed: 9 |
| Round | Opponent | W / L | Result |
| First Round | Sofia Kenin | Win | 6-3, 6-2 |
| Second Round | Tatjana Maria | Win | 4-6, 6-3, 6-2 |
| Third Round | Anastasija Sevastova | Loss | 3-6, 4-6 |
| Miami Open presented by Itau | ||
| Surface: Hard | Date: Mar. 20 - Apr. 1 | Seed: 21 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Claire Liu | Win | 6-0, 7-6 (7-0) |
| Third Round | Petra Martic | Win | 6-4, 6-3 |
| Fourth Round | Elina Svitolina | Loss | 5-7, 4-6 |
| BNP Paribas Open | ||
| Surface: Hard | Date: Mar. 7 - Mar. 18 | Seed: 16 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Maria Sakkari | Loss | 4-6, 2-6 |
| Australian Open | ||
| Surface: Hard | Date: Jan. 15 - Jan. 28 | Seed: 18 |
| Round | Opponent | W / L | Result |
| First Round | Aryna Sabalenka | Win | 6-7 (2-7), 6-4, 6-4 |
| Second Round | Camila Giorgi | Win | 5-7, 6-4, 6-1 |
| Third Round | Naomi Osaka | Loss | 4-6, 2-6 |
| Sydney International | ||
| Surface: Hard | Date: Jan. 7 - Jan. 13 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Veronica Cepede Royg | Win | 6-3, 6-4 |
| Second Round | Ellen Perez | Win | 7-6 (7-4), 6-1 |
| Quarterfinals | Barbora Strycova | Win | 6-3, 6-2 |
| Semifinals | Daria Gavrilova | Win | 3-6, 6-4, 6-2 |
| Final | Angelique Kerber | Loss | 4-6, 4-6 |
| Brisbane International presented by Suncorp | ||
| Surface: Hard | Date: Dec. 31 - Jan. 7 | Seed: 8 |
| Round | Opponent | W / L | Result |
| First Round | Lesia Tsurenko | Loss | 3-6, 2-6 |
