| ||||||||||||||
| Guadalajara Open Akron | ||
| Surface: Hard | Date: Oct. 17 - Oct. 23 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Elena Rybakina | Loss | 6-7 (5-7), 2-6 |
| San Diego Open | ||
| Surface: Hard | Date: Oct. 10 - Oct. 16 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Caroline Dolehide | Win | 6-3, 6-4 |
| Second Round | Donna Vekic | Loss | 3-6, 2-6 |
| AGEL Open 2022 | ||
| Surface: Hard | Date: Oct. 3 - Oct. 9 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Alycia Parks | Loss | 0-6, 6-7 (3-7) |
| Toray Pan Pacific Open | ||
| Surface: Hard | Date: Sep. 19 - Sep. 25 | Seed: 6 |
| Round | Opponent | W / L | Result |
| First Round | Isabella Shinikova | Win | 6-2, 6-1 |
| Second Round | Petra Martic | Loss | 3-6, 4-6 |
| US Open | ||
| Surface: Hard | Date: Aug. 29 - Sep. 11 | Seed: 22 |
| Round | Opponent | W / L | Result |
| First Round | Magda Linette | Win | 6-2, 4-6, 7-6 (10-8) |
| Second Round | Marie Bouzkova | Win | 6-3, 6-2 |
| Third Round | Belinda Bencic | Win | 5-7, 6-4, 6-3 |
| Fourth Round | Victoria Azarenka | Win | 7-5, 6-7 (5-7), 6-2 |
| Quarterfinals | Aryna Sabalenka | Loss | 1-6, 6-7 (4-7) |
| Western & Southern Open | ||
| Surface: Hard | Date: Aug. 14 - Aug. 21 | Seed: 14 |
| Round | Opponent | W / L | Result |
| First Round | Venus Williams | Win | |
| Second Round | Elise Mertens | Loss |
| National Bank Open presented by Rogers | ||
| Surface: Hard | Date: Aug. 8 - Aug. 14 | Seed: 14 |
| Round | Opponent | W / L | Result |
| First Round | Barbora Krejcikova | Win | |
| Second Round | Amanda Anisimova | Win | |
| Third Round | Maria Sakkari | Win | |
| Quarterfinals | Qinwen Zheng | Win | |
| Semifinals | Beatriz Haddad Maia | Loss |
| Mubadala Silicon Valley Classic | ||
| Surface: Hard | Date: Aug. 1 - Aug. 7 | Seed: 8 |
| Round | Opponent | W / L | Result |
| First Round | Katie Boulter | Win | |
| Second Round | Amanda Anisimova | Loss |
| Wimbledon | ||
| Surface: Grass | Date: Jun. 27 - Jul. 10 | Seed: 6 |
| Round | Opponent | W / L | Result |
| First Round | Tereza Martincova | Win | |
| Second Round | Katie Boulter | Loss |
| Rothesay International Eastbourne | ||
| Surface: Grass | Date: Jun. 19 - Jun. 25 | Seed: 4 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Katie Boulter | Loss |
| bett1open | ||
| Surface: Grass | Date: Jun. 13 - Jun. 19 | Seed: 4 |
| Round | Opponent | W / L | Result |
| First Round | Kaia Kanepi | Win | |
| Second Round | Bianca Andreescu | Win | |
| Quarterfinals | Coco Gauff | Loss |
| Roland Garros | ||
| Surface: Red Clay | Date: May 22 - Jun. 5 | Seed: 8 |
| Round | Opponent | W / L | Result |
| First Round | Tessah Andrianjafitrimo | Win | |
| Second Round | Leolia Jeanjean | Loss |
| Internationaux de Strasbourg | ||
| Surface: Clay | Date: May 15 - May 21 | Seed: 1 |
| Round | Opponent | W / L | Result |
| First Round | Marta Kostyuk | Win | |
| Second Round | Bernarda Pera | Win | |
| Quarterfinals | Maryna Zanevska | Win | |
| Semifinals | Kaja Juvan | Loss |
| Internazionali BNL d'Italia | ||
| Surface: Red Clay | Date: May 8 - May 15 | Seed: 6 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Jil Teichmann | Loss |
| Mutua Madrid Open | ||
| Surface: Hard | Date: Apr. 28 - May 8 | Seed: 5 |
| Round | Opponent | W / L | Result |
| First Round | Marie Bouzkova | Loss |
| Porsche Tennis Grand Prix | ||
| Surface: Clay | Date: Apr. 18 - Apr. 24 | Seed: 6 |
| Round | Opponent | W / L | Result |
| First Round | Petra Kvitova | Win | |
| Second Round | Liudmila Samsonova | Loss |
| Credit One Charleston Open | ||
| Surface: Green Clay | Date: Apr. 4 - Apr. 10 | Seed: 3 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Katarina Zavatska | Win | |
| Third Round | Ekaterina Alexandrova | Loss |
| Miami Open presented by Itau | ||
| Surface: Hard | Date: Mar. 22 - Apr. 3 | Seed: 6 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Anna Kalinskaya | Loss |
| BNP Paribas Open | ||
| Surface: Hard | Date: Mar. 9 - Mar. 20 | Seed: 7 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Danka Kovinic | Loss |
