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| Rolex Paris Masters | ||
| Surface: Hard | Date: Oct. 30 - Nov. 5 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Jordan Thompson | Win | 7-6 (7-5), 4-6, 6-2 |
| Second Round | Andrey Rublev | Loss | 4-6, 3-6 |
| Rakuten Japan Open Tennis Championships | ||
| Surface: Hard | Date: Oct. 15 - Oct. 22 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Marcos Giron | Loss | 6-7 (14-16), 6-4, 1-6 |
| Rolex Shanghai Masters | ||
| Surface: Hard | Date: Oct. 4 - Oct. 15 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Daniel Altmaier | Win | 6-4, 3-6, 7-6 (7-2) |
| Second Round | Casper Ruud | Loss | 5-7, 0-6 |
| China Open | ||
| Surface: Hard | Date: Sep. 28 - Oct. 4 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Juncheng Shang | Win | 5-7, 7-5, 6-1 |
| Second Round | Jannik Sinner | Loss | 2-6, 0-6 |
| Zhuhai Championships | ||
| Surface: Hard | Date: Sep. 20 - Sep. 26 | Seed: 8 |
| Round | Opponent | W / L | Result |
| First Round | Terence Atmane | Win | |
| Second Round | Lloyd Harris | Win | |
| Quarterfinals | Jan-Lennard Struff | Win | |
| Semifinals | Aslan Karatsev | Win | |
| Final | Karen Khachanov | Loss |
| US Open | ||
| Surface: Hard | Date: Aug. 28 - Sep. 10 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Stan Wawrinka | Loss |
| Western & Southern Open | ||
| Surface: Hard | Date: Aug. 13 - Aug. 20 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Gregoire Barrere | Win | |
| Second Round | Alexander Zverev | Loss |
| Omnium National Bank presented by Rogers | ||
| Surface: Hard | Date: Aug. 7 - Aug. 13 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Lorenzo Musetti | Loss |
| Citi Open | ||
| Surface: Hard | Date: Jul. 31 - Aug. 6 | Seed: 10 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Emil Ruusuvuori | Loss |
| Truist Atlanta Open presented by Fiserv | ||
| Surface: Hard | Date: Jul. 24 - Jul. 30 | Seed: 4 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Aleksandar Vukic | Loss |
| Wimbledon | ||
| Surface: Grass | Date: Jul. 3 - Jul. 16 | Seed: 24 |
| Round | Opponent | W / L | Result |
| First Round | Daniel Elahi Galan | Loss |
| French Open | ||
| Surface: Red Clay | Date: May 28 - Jun. 11 | Seed: 27 |
| Round | Opponent | W / L | Result |
| First Round | J.J. Wolf | Win | |
| Second Round | Max Purcell | Win | |
| Third Round | Thiago Seyboth Wild | Win | |
| Fourth Round | Tomas Martin Etcheverry | Loss |
| Internazionali BNL d'Italia | ||
| Surface: Red Clay | Date: May 10 - May 21 | Seed: 25 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Lorenzo Sonego | Loss |
| Mutua Madrid Open | ||
| Surface: Hard | Date: Apr. 26 - May 7 | Seed: 28 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Alex Molcan | Win | |
| Third Round | Andrey Rublev | Loss |
| Barcelona Open Banc Sabadell | ||
| Surface: Clay | Date: Apr. 17 - Apr. 23 | Seed: 16 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | David Goffin | Win | |
| Third Round | Jannik Sinner | Loss |
| Miami Open presented by Itau | ||
| Surface: Hard | Date: Mar. 22 - Apr. 2 | Seed: 28 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Alex Molcan | Loss |
| BNP Paribas Open | ||
| Surface: Hard | Date: Mar. 8 - Mar. 19 | Seed: 29 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Cristian Garin | Loss |
| Abierto Mexicano Telcel presentado por HSBC | ||
| Surface: Hard | Date: Feb. 26 - Mar. 4 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Frances Tiafoe | Loss |
| Delray Beach Open | ||
| Surface: Hard | Date: Feb. 13 - Feb. 19 | Seed: 5 |
| Round | Opponent | W / L | Result |
| First Round | Oscar Otte | Win | |
| Second Round | Mackenzie McDonald | Loss |
| Australian Open | ||
| Surface: Hard | Date: Jan. 15 - Jan. 29 | Seed: 31 |
| Round | Opponent | W / L | Result |
| First Round | Mikael Ymer | Win | |
| Second Round | Dalibor Svrcina | Win | |
| Third Round | Mackenzie McDonald | Win | |
| Fourth Round | Karen Khachanov | Loss |
| Adelaide International 1 | ||
| Surface: Hard | Date: Jan. 1 - Jan. 8 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Holger Rune | Win | |
| Second Round | Mackenzie McDonald | Win | |
| Quarterfinals | Alexei Popyrin | Win | |
| Semifinals | Sebastian Korda | Loss |
