2012 NCAA Football Big South Conference Schedule
| | Charleston Southern Buccaneers | | Sep 1 - L at Citadel, 14-49 | | Sep 8 - L vs. Jacksonville, 10-31 | | Sep 15 - L at Illinois, 0-44 | | Sep 22 - W at Shorter, 23-20 | | Sep 29 - Open | | Oct 6 - L at Stony Brook, 7-49 | | Oct 13 - W vs. Va Military, 32-14 | | Oct 20 - W vs. Presbyterian, 31-21 | | Oct 27 - W vs. Edward Waters, 42-7 | | Nov 3 - L at Liberty, 12-26 | | Nov 10 - W vs. Gardner-Webb, 28-10 | | Nov 17 - L at Coastal Carolina, 20-41 |
| | Coastal Carolina Chanticleers | | Sep 1 - W vs. NC A&T, 29-13 | | Sep 8 - W at Furman, 47-45 3OT | | Sep 15 - L vs. Eastern Ky, 17-35 | | Sep 22 - L at Toledo, 28-38 | | Sep 29 - L at Appalachian St, 14-55 | | Oct 6 - Open | | Oct 13 - L vs. Stony Brook, 21-27 | | Oct 20 - W at Va Military, 34-7 | | Oct 27 - W vs. Liberty, 36-12 | | Nov 3 - W at Gardner-Webb, 55-33 | | Nov 10 - W at Presbyterian, 65-7 | | Nov 17 - W vs. Char Southern, 41-20 | | Nov 24 - W at Bethune-Cookman, 24-14 | | Dec 1 - L at Old Dominion, 35-63 |
| | Gardner-Webb Runnin' Bulldogs | | Sep 1 - L vs. Wofford, 7-34 | | Sep 8 - L at Richmond, 8-41 | | Sep 15 - L vs. Samford, 23-44 | | Sep 22 - L at Pittsburgh, 10-55 | | Sep 29 - Open | | Oct 6 - L at Liberty, 35-42 | | Oct 13 - W vs. MidAmerica Nazarene, 30-28 | | Oct 20 - L at Stony Brook, 10-41 | | Oct 27 - W vs. Va Military, 38-7 | | Nov 3 - L vs. Coastal Carolina, 33-55 | | Nov 10 - L at Char Southern, 10-28 | | Nov 17 - W vs. Presbyterian, 21-15 |
| | Liberty Flames | | Sep 1 - L at Wake Forest, 17-20 | | Sep 8 - L vs. Norfolk State, 24-31 | | Sep 15 - L at Montana, 14-34 | | Sep 22 - L vs. Lehigh, 26-28 | | Sep 29 - Open | | Oct 6 - W vs. Gardner-Webb, 42-35 | | Oct 13 - W at Presbyterian, 56-7 | | Oct 20 - W vs. Concord, 21-13 | | Oct 27 - L at Coastal Carolina, 12-36 | | Nov 3 - W vs. Char Southern, 26-12 | | Nov 10 - W vs. Stony Brook, 28-14 | | Nov 17 - W at Va Military, 33-14 |
| | Presbyterian Blue Hose | | Sep 1 - W vs. Brevard, 45-10 | | Sep 8 - L at Georgia Tech, 3-59 | | Sep 15 - L at Vanderbilt, 0-58 | | Sep 22 - L vs. Furman, 21-31 | | Sep 29 - W at Davidson, 28-13 | | Oct 6 - L at Va Military, 7-17 | | Oct 13 - L vs. Liberty, 7-56 | | Oct 20 - L at Char Southern, 21-31 | | Oct 27 - L vs. Stony Brook, 17-56 | | Nov 3 - Open | | Nov 10 - L vs. Coastal Carolina, 7-65 | | Nov 17 - L at Gardner-Webb, 15-21 |
| | Virginia Military Keydets | | Sep 1 - L at Delaware State, 10-17 | | Sep 8 - W vs. Chowan, 24-17 | | Sep 15 - L vs. Richmond, 6-47 | | Sep 22 - L at Navy, 3-41 | | Sep 29 - Open | | Oct 6 - W vs. Presbyterian, 17-7 | | Oct 13 - L at Char Southern, 14-32 | | Oct 20 - L vs. Coastal Carolina, 7-34 | | Oct 27 - L at Gardner-Webb, 7-38 | | Nov 3 - L at Stony Brook, 7-45 | | Nov 10 - L vs. Citadel, 24-27 | | Nov 17 - L vs. Liberty, 14-33 |
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