|
| 4th Quarter |
|
| San Francisco at 15:00 |
| 2nd and 6 at BUF 17 | 4th quarter under way. |
| 2nd and 6 at BUF 17 | Frank Gore up the middle to the Buffalo 10 for 7 yards. |
| 1st and 10 at BUF 10 | 10-yard pass from Alex Smith to Mario Manningham. |
| | David Akers extra point is good. |
| | David Akers kicks 65 yards from the San Francisco 35 into the end zone for a touchback. |
| Buffalo at 13:30 |
| 1st and 10 at BUF 20 | Ryan Fitzpatrick pass to Stevie Johnson to the Buffalo 22 for 2 yards. |
| 2nd and 8 at BUF 22 | Ryan Fitzpatrick pass incomplete to Scott Chandler. |
| 3rd and 8 at BUF 22 | Ryan Fitzpatrick pass incomplete to Stevie Johnson. |
| 4th and 8 at BUF 22 | Shawn Powell punted 56 yards from the Buffalo 22 to the San Francisco 22. Ted Ginn Jr. returned to the San Francisco 33 for 11 yards. |
| San Francisco at 12:25 |
| 1st and 10 at SFX 33 | Frank Gore up the middle to the San Francisco 43 for 10 yards. |
| 1st and 10 at SFX 43 | Kendall Hunter rushed left to the Buffalo 46 for 11 yards. |
| 1st and 10 at BUF 46 | Alex Smith pass incomplete to Randy Moss. |
| 2nd and 10 at BUF 46 | Alex Smith pass incomplete to Vernon Davis. |
| 3rd and 10 at BUF 46 | Alex Smith scrambled to the Buffalo 38 for 8 yards. |
| 4th and 2 at BUF 38 | Alex Smith rushed wide left to the Buffalo 21 for 17 yards. |
| 1st and 10 at BUF 21 | Defensive penalty on Buffalo, Mark Anderson, Neutral Zone Infraction, 5 yards, enforced at the Buffalo 21. |
| 1st and 5 at BUF 16 | 16-yard run by Colin Kaepernick. |
| | David Akers extra point is good. |
| | David Akers kicks 65 yards from the San Francisco 35 into the end zone for a touchback. |
| Buffalo at 9:25 |
| 1st and 10 at BUF 20 | Fred Jackson rushed right to the Buffalo 22 for 2 yards. |
| 2nd and 8 at BUF 22 | Ryan Fitzpatrick pass to Stevie Johnson to the Buffalo 22 for no gain. |
| 3rd and 8 at BUF 22 | Ryan Fitzpatrick pass to Donald Jones to the Buffalo 27 for 5 yards. |
| 4th and 3 at BUF 27 | Shawn Powell punted 50 yards from the Buffalo 27 to the San Francisco 23. Ted Ginn Jr. returned to the San Francisco 31 for 8 yards. |
| San Francisco at 7:00 |
| 1st and 10 at SFX 31 | Kendall Hunter rushed to the San Francisco 36 for 5 yards. |
| 2nd and 5 at SFX 36 | Colin Kaepernick scrambled to the San Francisco 38 for 2 yards. |
| 3rd and 3 at SFX 38 | Colin Kaepernick pass to Kyle Williams to the San Francisco 45 for 7 yards. |
| 1st and 10 at SFX 45 | Kendall Hunter rushed right to the Buffalo 49 for 6 yards. |
| 2nd and 4 at BUF 49 | Kendall Hunter rushed left to the Buffalo 23 for 26 yards. |
| 1st and 10 at BUF 23 | Kendall Hunter up the middle to the Buffalo 20 for 3 yards. |
| 2nd and 7 at BUF 20 | Kendall Hunter up the middle to the Buffalo 15 for 5 yards. |
| 3rd and 2 at BUF 15 | Kendall Hunter rushed left to the Buffalo 12 for 3 yards. |
| 1st and 10 at BUF 12 | Kendall Hunter rushed wide left to the Buffalo 7 for 5 yards. |
| 2nd and 5 at BUF 7 | Anthony Dixon up the middle to the Buffalo 3 for 4 yards. |
| 3rd and 1 at BUF 3 | 3-yard run by Anthony Dixon. |
| | David Akers extra point is good. |
| | David Akers kicked off 55 yards from the San Francisco 35 to the Buffalo 10. Brad Smith to the Buffalo 38 for 28 yards. |
| Buffalo at 0:31 |
| 1st and 10 at BUF 38 | Fred Jackson rushed to the Buffalo 42 for 4 yards. |
| 2nd and 6 at BUF 42 | Fred Jackson rushed to the Buffalo 43 for 1 yard. |
