| Scoring Summary |
| 1st Quarter |
| San Francisco Touchdown - 7-yard pass from Alex Smith to Michael Crabtree. (Joe Nedney extra point is good). 7:53 Time Remaining. (11 plays, 51 yards. Time of Drive: 7:07). |
| Philadelphia Touchdown - 8-yard pass from Kevin Kolb to Brent Celek. (David Akers extra point is good). 2:23 Time Remaining. (10 plays, 75 yards. Time of Drive: 5:30). |
| 2nd Quarter |
| Philadelphia Field Goal - 33-yarder by David Akers. 11:45 Time Remaining. (7 plays, 31 yards. Time of Drive: 3:31). |
| Philadelphia Touchdown - 29-yard run by LeSean McCoy. (David Akers extra point is good). 1:53 Time Remaining. (3 plays, 53 yards. Time of Drive: 1:10). |
| San Francisco Field Goal - 50-yarder by Joe Nedney. 0:43 Time Remaining. (7 plays, 48 yards. Time of Drive: 1:10). |
| 3rd Quarter |
No Scoring | | 4th Quarter |
| Philadelphia Touchdown - 52-yard fumble return by Quintin Mikell. (David Akers extra point is good). 13:26 Time Remaining. |
| San Francisco Touchdown - 7-yard pass from Alex Smith to Vernon Davis. (Joe Nedney extra point is good). 7:35 Time Remaining. (6 plays, 69 yards. Time of Drive: 3:35). |
| Philadelphia Field Goal - 45-yarder by David Akers. 4:35 Time Remaining. (6 plays, 37 yards. Time of Drive: 3:00). |
| San Francisco Touchdown - 1-yard pass from Alex Smith to Frank Gore. (Joe Nedney extra point is good). 2:02 Time Remaining. (7 plays, 36 yards. Time of Drive: 2:33). |