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| 4th Quarter |
|
| Houston at 15:00 |
| 2nd and 2 at BUF 28 | 4th quarter under way. |
| 2nd and 2 at BUF 28 | Arian Foster rushed right to the Buffalo 25 for 3 yards. |
| 1st and 10 at BUF 25 | Arian Foster rushed right to the Buffalo 27 for -2 yards. |
| 2nd and 12 at BUF 27 | Matt Schaub pass to Andre Johnson to the Buffalo 9 for 18 yards. |
| 1st and 9 at BUF 9 | Arian Foster rushed left to the Buffalo 11 for -2 yards. |
| 2nd and 11 at BUF 11 | Matt Schaub pass to Garrett Graham to the Buffalo 5 for 6 yards. |
| 3rd and 5 at BUF 5 | 5-yard pass from Matt Schaub to Garrett Graham. |
| | Shayne Graham extra point is good. |
| | Shayne Graham kicked off 49 yards from the Houston 35 to the Buffalo 16. Brad Smith to the Buffalo 31 for 15 yards. |
| Buffalo at 10:54 |
| 1st and 10 at BUF 31 | Ryan Fitzpatrick pass to Donald Jones to the Buffalo 33 for 2 yards. |
| 2nd and 8 at BUF 33 | Ryan Fitzpatrick pass incomplete to Fred Jackson. |
| 3rd and 8 at BUF 33 | Ryan Fitzpatrick pass incomplete to Scott Chandler. |
| 4th and 8 at BUF 33 | Shawn Powell punted the ball 57 yards, out of bounds at the Houston 10. |
| Houston at 9:43 |
| 1st and 10 at HOU 10 | Arian Foster up the middle to the Houston 13 for 3 yards. |
| 2nd and 7 at HOU 13 | Matt Schaub pass to Andre Johnson to the Houston 22 for 9 yards. |
| 1st and 10 at HOU 22 | Arian Foster rushed left to the Houston 27 for 5 yards. |
| 2nd and 5 at HOU 27 | Arian Foster rushed left to the Houston 33 for 6 yards. |
| 1st and 10 at HOU 33 | Arian Foster rushed right to the Houston 35 for 2 yards. |
| 2nd and 8 at HOU 35 | Matt Schaub pass to James Casey to the Houston 47 for 12 yards. |
| 1st and 10 at HOU 47 | Arian Foster rushed left to the Buffalo 34 for 19 yards. |
| 1st and 10 at BUF 34 | Justin Forsett rushed left for no gain. |
| 2nd and 10 at BUF 34 | Justin Forsett rushed left to the Buffalo 29 for 5 yards. |
| 3rd and 5 at BUF 29 | Arian Foster rushed right to the Buffalo 30 for -1 yards. |
| 4th and 6 at BUF 30 | Matt Schaub pass incomplete to Andre Johnson. |
| Buffalo at 4:24 |
| 1st and 10 at BUF 30 | Ryan Fitzpatrick pass incomplete to Stevie Johnson. |
| 2nd and 10 at BUF 30 | Ryan Fitzpatrick pass to Fred Jackson to the Buffalo 35 for 5 yards. |
| 3rd and 5 at BUF 35 | Ryan Fitzpatrick pass incomplete to Ruvell Martin. |
| 4th and 5 at BUF 35 | Ryan Fitzpatrick pass to Scott Chandler to the Houston 49 for 16 yards. |
| 1st and 10 at HOU 49 | Ryan Fitzpatrick pass incomplete to Donald Jones. |
| 2nd and 10 at HOU 49 | Ryan Fitzpatrick scrambled to the Houston 38 for 11 yards. |
| 1st and 10 at HOU 38 | Ryan Fitzpatrick rushed left to the Houston 34 for 4 yards. Ryan Fitzpatrick fumble recovered by Quintin Demps at the Houston 32 returned for no gain. |
| Houston at 2:40 |
| 1st and 10 at HOU 32 | Justin Forsett rushed left to the Houston 31 for -1 yards. |
| 2nd and 11 at HOU 31 | Justin Forsett rushed right to the Houston 37 for 6 yards. |
| 3rd and 5 at HOU 37 | Justin Forsett rushed left to the Houston 34 for -3 yards. |
| 4th and 8 at HOU 34 | Donnie Jones punted 43 yards from the Houston 34 to the Buffalo 23. Leodis McKelvin returned to the Buffalo 22 for -1 yards. |
| Buffalo at 0:58 |
| 1st and 10 at BUF 22 | Ryan Fitzpatrick pass to C.J. Spiller to the Buffalo 28 for 6 yards. |
| 2nd and 4 at BUF 28 | Ryan Fitzpatrick pass to T.J. Graham to the Buffalo 33 for 5 yards. |
| 1st and 10 at BUF 33 | Ryan Fitzpatrick pass to C.J. Spiller to the Buffalo 46 for 13 yards. |
| 1st and 10 at BUF 46 | Offensive penalty on Buffalo, Cordy Glenn, False Start, 5 yards, enforced at the Buffalo 46. |
| 1st and 15 at BUF 41 | Ryan Fitzpatrick sacked by Whitney Mercilus for -2 yards. |
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