2006 NCAA Football Big South Conference Schedule
| | Charleston Southern Buccaneers | | Sep 2 - W at Presbyterian, 21-13 | | Sep 9 - W at Citadel, 38-35 2OT | | Sep 16 - W vs. Wingate, 20-17 | | Sep 23 - Open | | Sep 30 - W vs. North Greenville, 20-10 | | Oct 7 - W at Savannah State, 38-13 | | Oct 14 - W vs. Edward Waters, 47-0 | | Oct 21 - W vs. Va Military, 27-22 | | Oct 28 - W vs. Georgetown, 24-10 | | Nov 4 - W vs. Gardner-Webb, 28-14 | | Nov 11 - L at Liberty, 20-34 | | Nov 18 - L at Coastal Carolina, 17-31 |
| | Coastal Carolina Chanticleers | | Sep 2 - L vs. Elon, 20-23 | | Sep 9 - W at Wofford, 41-38 | | Sep 16 - L at Ga Southern, 21-38 | | Sep 23 - W vs. SC State, 33-14 | | Sep 30 - W at Winston-Salem St, 31-12 | | Oct 7 - W vs. Furman, 29-27 | | Oct 14 - W at Va Military, 31-27 | | Oct 21 - Open | | Oct 28 - W vs. Liberty, 28-26 | | Nov 4 - W vs. Savannah State, 66-6 | | Nov 11 - W at Gardner-Webb, 52-24 | | Nov 18 - W vs. Char Southern, 31-17 | | Nov 25 - L at Appalachian St, 28-45 |
| | Gardner-Webb Runnin' Bulldogs | | Sep 2 - W at Jacksonville, 49-14 | | Sep 9 - W vs. Tenn Tech, 30-26 | | Sep 16 - L at Tenn-Martin, 9-35 | | Sep 23 - L vs. Appalachian St, 6-41 | | Sep 30 - W at SE Louisiana, 28-21 | | Oct 7 - Open | | Oct 14 - W vs. Glenville St, 31-23 | | Oct 21 - W at Liberty, 27-24 | | Oct 28 - W vs. Va Military, 35-31 | | Nov 4 - L at Char Southern, 14-28 | | Nov 11 - L vs. Coastal Carolina, 24-52 | | Nov 18 - L vs. Wofford, 17-34 |
| | Liberty Flames | | Aug 31 - W vs. St Pauls (VA), 27-0 | | Sep 9 - W vs. Glenville St, 31-7 | | Sep 16 - L at Towson, 3-10 | | Sep 23 - W at Savannah State, 28-0 | | Sep 30 - L at Wake Forest, 14-34 | | Oct 7 - Open | | Oct 14 - L vs. William & Mary, 13-14 | | Oct 21 - L vs. Gardner-Webb, 24-27 | | Oct 28 - L at Coastal Carolina, 26-28 | | Nov 4 - W vs. Western Carolina, 21-0 | | Nov 11 - W vs. Char Southern, 34-20 | | Nov 18 - W at Va Military, 38-32 |
| | Presbyterian Blue Hose | | Aug 26 - W at West Georgia, 10-0 | | Sep 2 - L vs. Char Southern, 13-21 | | Sep 9 - W at Fayetteville St, 7-6 | | Sep 16 - L at Elon, 0-28 | | Sep 23 - Open | | Sep 30 - W vs. Lenoir-Rhyne, 24-13 | | Oct 7 - L vs. Wingate, 9-14 | | Oct 14 - W at Tusculum, 30-21 | | Oct 21 - W at Mars Hill, 21-14 OT | | Oct 28 - W vs. Carson-Newman, 28-7 | | Nov 4 - L at Catawba, 14-21 | | Nov 11 - W vs. Newberry, 10-0 |
| | Virginia Military Keydets | | Sep 2 - W vs. Davidson, 20-19 | | Sep 9 - L at Norfolk State, 19-32 | | Sep 16 - L at Richmond, 7-58 | | Sep 23 - L at William & Mary, 6-38 | | Sep 30 - L vs. James Madison, 7-45 | | Oct 7 - L at Army, 7-62 | | Oct 14 - L vs. Coastal Carolina, 27-31 | | Oct 21 - L at Char Southern, 22-27 | | Oct 28 - L at Gardner-Webb, 31-35 | | Nov 4 - Open | | Nov 11 - L at Citadel, 21-48 | | Nov 18 - L vs. Liberty, 32-38 |
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