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W:H.Kuroda(10-8) L:A.Ranaudo(3-1)
HR: BOS- None NYY- B.McCann (17)

American League Preview from The Sports Network

Wednesday, September 3 (All times Eastern)

Boston Red Sox (60-77) at New York Yankees (70-65), 7:05 p.m.

Probable Starting Pitchers: Boston - Anthony Ranaudo (3-0, New York - Hiroki Kuroda (9-8, 3.88)

( - Time is running out for the New York Yankees and reality is starting to set in that Derek Jeter's final season will likely end without a postseason appearance.

The Yankees try to keep their fading hopes alive on Wednesday when they continue a three-game series with the Boston Red Sox at Yankee Stadium..

New York lost its third straight game in Tuesday's opener, as Xander Bogaerts had four hits, including one of three Boston home runs, and two RBI to lead the Red Sox to a 9-4 rout.

Mookie Betts and Yoenis Cespedes each finished 3-for-5 for Boston, with Betts clubbing a solo homer and Cespedes delivering an RBI double. Daniel Nava also homered, connecting on a three-run blast that helped stake Boston to a 6-0 lead and ultimately hand the Yankees their fifth loss in seven games.

"This season definitely has not been the way that we all wanted, we all expected it to be. But there's a lot of talent coming up and hopefully we can blend in together and have a good future," Bogaerts said.

This defeat was a costly one as well for the Yankees, who fell five games behind Detroit in the race for the AL's final wild card spot after the Tigers rallied to top Cleveland on Tuesday.

Joe Kelly (1-1) benefited from the early run support to notch his first victory since coming to Boston in the July 31 trade that sent John Lackey to St. Louis. The ex-Cardinal worked around four walks to allow three runs over 6 2/3 innings and struck out six.

Yankees starter Shane Greene (4-2), however, was shelled for six runs on six hits before departing with two out in the top of the third.

Martin Prado and Brian McCann both homered and collected two hits to pace New York offensively. Jeter also had an RBI single in the setback.

"These series are extremely important and it's not how you want to start off a homestand," Yankees manager Joe Girardi said.

Now the Yanks go up against undefeated right-hander Anthony Ranaudo, who has won all three of his big league starts and has pitched to a 4.50 ERA. Ranaudo defeated Tampa Bay on Friday, holding them to three runs and five hits over six innings.

Wednesday will be the New Jersey native's first time pitching at Yankee Stadium.

"It's going to be fun," Ranaudo said. "I can't even describe how excited I'm going to be. It will be pretty interesting tonight when I put my head on that pillow and see if I can fall asleep. There will be a lot of emotions, but like I said, I'm going to try to take it like it's another game and do the things that have made me successful this year to this point, try to go as deep as I can into the game, put our team in a position to win."

New York, meanwhile, will turn to righty Hiroki Kuroda, who is 9-8 with a 3.88 ERA. Kuroda did not get a decision in Detroit on Thursday, but pitched well, surrendering just two runs and four hits in seven innings of his team's 3-2 loss.

Kuroda has struggled against the Red Sox, posting a 4-5 mark to go along with a 4.18 ERA in 18 starts. He did beat them in his only other start against them this season, though.

New York is 8-6 versus the Red Sox this season, but the rivals are an even 19-19 against one another since Sept. 12, 2012.

09/03 10:28:13 ET