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| 4th Quarter |
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| San Francisco at 15:00 |
| 1st and 10 at ARI 22 | 4th quarter under way. |
| 1st and 10 at ARI 22 | Colin Kaepernick pass to Frank Gore to the Arizona 8 for 14 yards. |
| 1st and 8 at ARI 8 | Frank Gore rushed left to the Arizona 7 for 1 yard. |
| 2nd and 7 at ARI 7 | Frank Gore rushed right to the Arizona 2 for 5 yards. |
| 3rd and 2 at ARI 2 | 2-yard run by Frank Gore. |
| | David Akers extra point is good. |
| | David Akers kicks 65 yards from the San Francisco 35 into the end zone for a touchback. |
| Arizona at 12:49 |
| 1st and 10 at ARI 20 | Brian Hoyer pass to Michael Floyd to the Arizona 25 for 5 yards. Michael Floyd fumble recovered by Donte Whitner at the Arizona 25 returned for no gain. |
| San Francisco at 12:43 |
| 1st and 10 at ARI 25 | Colin Kaepernick pass incomplete to Michael Crabtree. |
| 2nd and 10 at ARI 34 | Frank Gore up the middle to the Arizona 30 for 4 yards. |
| 3rd and 6 at ARI 21 | Colin Kaepernick pass incomplete to Michael Crabtree. |
| 4th and 6 at ARI 30 | Colin Kaepernick pass to Michael Crabtree to the Arizona 23 for 7 yards. |
| 1st and 10 at ARI 23 | Frank Gore rushed right to the Arizona 17 for 6 yards. |
| 2nd and 4 at ARI 17 | Defensive penalty on Arizona, Nick Eason, Flagrant Face Mask, 9 yards, enforced at the Arizona 17. |
| 1st and 10 at ARI 8 | Anthony Dixon rushed left to the Arizona 4 for 4 yards. |
| 2nd and 6 at ARI 4 | Anthony Dixon rushed right to the Arizona 3 for 1 yard. |
| 3rd and 5 at ARI 3 | Colin Kaepernick scrambled to the Arizona 8 for -5 yards. |
| 4th and 10 at ARI 8 | 26-yarder by David Akers. |
| | David Akers kicked off 67 yards from the San Francisco 35 to the Arizona -2. LaRod Stephens-Howling to the Arizona 19 for 21 yards. |
| Arizona at 8:37 |
| 1st and 10 at ARI 19 | Brian Hoyer pass to Andre Roberts to the Arizona 22 for 3 yards. |
| 2nd and 7 at ARI 22 | Brian Hoyer pass to Jeff King to the Arizona 28 for 6 yards. |
| 3rd and 1 at ARI 28 | Brian Hoyer pass to Jeff King to the Arizona 30 for 2 yards. |
| 1st and 10 at ARI 30 | Brian Hoyer pass to Michael Floyd to the Arizona 36 for 6 yards. |
| 2nd and 4 at ARI 36 | Brian Hoyer pass to Andre Roberts to the Arizona 39 for 3 yards. |
| 3rd and 1 at ARI 39 | William Powell up the middle to the Arizona 41 for 2 yards. |
| 1st and 10 at ARI 41 | Brian Hoyer pass intended for Larry Fitzgerald intercepted by Tarell Brown at the San Francisco 43 returned to the Arizona 45 for 12 yards. |
| San Francisco at 5:57 |
| 1st and 10 at ARI 45 | Offensive penalty on San Francisco, Aldon Smith, Unnecessary Roughness, 15 yards, enforced at the Arizona 45. |
| 1st and 10 at SFX 40 | Anthony Dixon rushed left to the San Francisco 41 for 1 yard. |
| 2nd and 9 at SFX 41 | LaMichael James rushed left for no gain. |
| 3rd and 9 at SFX 41 | Alex Smith pass to Bruce Miller to the San Francisco 47 for 6 yards. |
| 4th and 3 at SFX 47 | Andy Lee punted 36 yards from the San Francisco 47 to the Arizona 17. Andre Roberts returned to the Arizona 22 for 5 yards. |
| Arizona at 3:33 |
| 1st and 10 at ARI 22 | Brian Hoyer pass to Jeff King to the Arizona 24 for 2 yards. |
| 2nd and 8 at ARI 24 | Brian Hoyer pass to Michael Floyd to the San Francisco 23 for 53 yards. |
| 1st and 10 at SFX 23 | Brian Hoyer pass incomplete to Michael Floyd. |
| 2nd and 10 at SFX 23 | Brian Hoyer pass incomplete to Michael Floyd. |
| 3rd and 10 at SFX 23 | Offensive penalty on Arizona, Senio Kelemete, Holding/Illegal Use of Hands, 10 yards, enforced at the San Francisco 23. |
| 3rd and 20 at SFX 33 | Brian Hoyer pass to William Powell to the San Francisco 37 for -4 yards. |
| 4th and 24 at SFX 37 | 37-yard pass from Brian Hoyer to Michael Floyd. |
| | Jay Feely extra point is good. |
| | Jay Feely failed the onside kick recovered by Randy Moss kicked off 4 yards from the Arizona 35 to the Arizona 39. Randy Moss for no gain. |
| San Francisco at 1:39 |
| 1st and 10 at ARI 39 | LaMichael James rushed right to the Arizona 29 for 10 yards. |
| 1st and 10 at ARI 29 | Alex Smith kneels to the Arizona 30 for -1 yards. |
| 2nd and 11 at ARI 30 | Alex Smith kneels to the Arizona 31 for -1 yards. |