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As of 1:40 p.m. (et)

NFL

Brian Hoyer will be the starting quarterback for the Cleveland Browns to open the season. Coach Mike Pettine made the announcement on Wednesday morning, selecting Hoyer over rookie Johnny Manziel. Hoyer started each of the Browns' first two preseason games and will open the season under center when Cleveland plays its first regular-season game on Sept. 7 against Pittsburgh. The Michigan State product also started three games for the Browns last year, but a torn ACL in the first quarter of a Week 5 victory over Buffalo ended his season. He led Cleveland to a pair of wins in his first two starts and completed 57-of-96 passes for 615 yards with five touchdowns and three interceptions in his limited action last year.

The Pittsburgh Steelers have re-signed defensive end Brett Keisel to a two- year contract. Keisel has played his entire 12-year career with the Steelers, who selected him in the seventh round of the 2002 NFL Draft. However, he had not received a contract offer as an unrestricted free agent this summer and a Pittsburgh newspaper reported that the Arizona Cardinals were set to make him a proposal earlier this week. Keisel, a 2010 Pro Bowl choice, has started 110 of the 144 games he has played with Pittsburgh and has helped the Steelers to a pair of Super Bowl titles. He has 29 career sacks with seven forced fumbles and seven fumble recoveries.

BASEBALL

Former All-Star pitcher Curt Schilling said chewing smokeless tobacco gave him cancer. Schilling, appearing on WEEI radio in Boston, said he is in remission after undergoing treatment for squamous cell carcinoma. He revealed his diagnosis in February with a statement through ESPN and spoke publicly about it for the first time on Wednesday. The 47-year-old six-time All-Star said he chewed tobacco for about 30 years and firmly believes it is the reason he developed cancer. The news about Schilling comes just two months after Hall of Famer Tony Gwynn died after battling cancer of the salivary gland following his use of smokeless tobacco.

TENNIS

Former champion Novak Djokovic has been installed as the top seed for the upcoming U.S. Open, while five-time winner Roger Federer will be the second seed for the year's final tennis major championship. Djokovic is the current world No. 1 and is coming off a Wimbledon championship. He captured his lone U.S. Open title in 2011 and was last year's runner-up to Rafael Nadal, who announced earlier this week that he will not defend his title because of a wrist injury. Federer, who lost to Djokovic in the final at the All England Club earlier this summer, is coming off his 80th career title after winning the Cincinnati tune-up last week. Australian Open winner Stan Wawrinka is the third seed at Flushing Meadows, followed by David Ferrer and Milos Raonic.

Next check of Sports News at 3:30 - 3:45 p.m. (et) 08/20 13:46:23 ET