| July 2021 |
| Date | Time | Opponent | Venue | Result |
| Sat. 17 | 4:15 PM PT5:15 PM MT6:15 PM CT7:15 PM ET23:15 GMT0:15 23:15 11:15 PM 1:15 KSA10:15 AM AET4:45 (+1) IST6:45 PM VEN3:15 (+1) UAE7:15 AM SST7:15 6:15 4:15 PM MST5:15 PM CST6:15 PM EST19:15 ET18:15 20:15 BRT19:15 6:15 PM CT | Racing Club | Estadio Jose Amalfitani | D 0-0 |
| Sun. 25 | 11:45 AM PT12:45 PM MT1:45 PM CT2:45 PM ET18:45 GMT19:45 18:45 6:45 PM 20:45 KSA5:45 AM AET0:15 (+1) IST2:15 PM VEN22:45 UAE2:45 AM SST2:45 1:45 11:45 AM MST12:45 PM CST1:45 PM EST14:45 ET13:45 15:45 BRT14:45 1:45 PM CT | Rosario Central | Estadio Dr. Lisandro de la Torre | L 0-1 |
| Wed. 28 | 12:30 PM PT1:30 PM MT2:30 PM CT3:30 PM ET19:30 GMT20:30 19:30 7:30 PM 21:30 KSA6:30 AM AET1:00 (+1) IST3:00 PM VEN23:30 UAE3:30 AM SST3:30 2:30 12:30 PM MST1:30 PM CST2:30 PM EST15:30 ET14:30 16:30 BRT15:30 2:30 PM CT | Defensa y Justicia | Estadio Jose Amalfitani | D 0-0 |
| August 2021 |
| Date | Time | Opponent | Venue | Result |
| Mon. 2 | 5:15 PM PT6:15 PM MT7:15 PM CT8:15 PM ET0:15 (+1) GMT1:15 0:15 12:15 AM 2:15 KSA11:15 AM AET5:45 (+1) IST7:45 PM VEN4:15 (+1) UAE8:15 AM SST8:15 7:15 5:15 PM MST6:15 PM CST7:15 PM EST20:15 ET19:15 21:15 BRT20:15 7:15 PM CT | Atlético Tucumán | Estadio Monumental Presidente Jose Fierro | D 0-0 |
| Sun. 8 | 11:45 AM PT12:45 PM MT1:45 PM CT2:45 PM ET18:45 GMT19:45 18:45 6:45 PM 20:45 KSA5:45 AM AET0:15 (+1) IST2:15 PM VEN22:45 UAE2:45 AM SST2:45 1:45 11:45 AM MST12:45 PM CST1:45 PM EST14:45 ET13:45 15:45 BRT14:45 1:45 PM CT | Colón | Estadio Jose Amalfitani | L 0-1 |
| Sat. 14 | 2:00 PM PT3:00 PM MT4:00 PM CT5:00 PM ET21:00 GMT22:00 21:00 9:00 PM 23:00 KSA8:00 AM AET2:30 (+1) IST4:30 PM VEN1:00 (+1) UAE5:00 AM SST5:00 4:00 2:00 PM MST3:00 PM CST4:00 PM EST17:00 ET16:00 18:00 BRT17:00 4:00 PM CT | River Plate | Estadio Monumental Antonio Vespucio Liberti | L 0-2 |
| Sat. 21 | 11:45 AM PT12:45 PM MT1:45 PM CT2:45 PM ET18:45 GMT19:45 18:45 6:45 PM 20:45 KSA5:45 AM AET0:15 (+1) IST2:15 PM VEN22:45 UAE2:45 AM SST2:45 1:45 11:45 AM MST12:45 PM CST1:45 PM EST14:45 ET13:45 15:45 BRT14:45 1:45 PM CT | Lanús | Estadio Jose Amalfitani | W 5-1 |
| Wed. 25 | 2:45 PM PT3:45 PM MT4:45 PM CT5:45 PM ET21:45 GMT22:45 21:45 9:45 PM 23:45 KSA8:45 AM AET3:15 (+1) IST5:15 PM VEN1:45 (+1) UAE5:45 AM SST5:45 4:45 2:45 PM MST3:45 PM CST4:45 PM EST17:45 ET16:45 18:45 BRT17:45 4:45 PM CT | Huracán | Estadio Tomas Adolfo Duco | D 1-1 |
| Sun. 29 | 2:00 PM PT3:00 PM MT4:00 PM CT5:00 PM ET21:00 GMT22:00 21:00 9:00 PM 23:00 KSA8:00 AM AET2:30 (+1) IST4:30 PM VEN1:00 (+1) UAE5:00 AM SST5:00 4:00 2:00 PM MST3:00 PM CST4:00 PM EST17:00 ET16:00 18:00 BRT17:00 4:00 PM CT | Godoy Cruz | Estadio Jose Amalfitani | W 3-0 |
| September 2021 |
| Date | Time | Opponent | Venue | Result |
| Mon. 6 | 4:15 PM PT5:15 PM MT6:15 PM CT7:15 PM ET23:15 GMT0:15 23:15 11:15 PM 1:15 KSA10:15 AM AET4:45 (+1) IST6:45 PM VEN3:15 (+1) UAE7:15 AM SST7:15 6:15 4:15 PM MST5:15 PM CST6:15 PM EST19:15 ET18:15 20:15 BRT19:15 6:15 PM CT | Union Santa Fe | Estadio Jose Amalfitani | W 4-0 |
| Mon. 13 | 5:00 PM PT6:00 PM MT7:00 PM CT8:00 PM ET0:00 (+1) GMT1:00 0:00 12:00 AM 2:00 KSA11:00 AM AET5:30 (+1) IST7:30 PM VEN4:00 (+1) UAE8:00 AM SST8:00 7:00 5:00 PM MST6:00 PM CST7:00 PM EST20:00 ET19:00 21:00 BRT20:00 7:00 PM CT | Gimnasia LP | Estadio Juan Carmelo Zerillo | D 0-0 |
| Sat. 18 | 11:45 AM PT12:45 PM MT1:45 PM CT2:45 PM ET18:45 GMT19:45 18:45 6:45 PM 20:45 KSA5:45 AM AET0:15 (+1) IST2:15 PM VEN22:45 UAE2:45 AM SST2:45 1:45 11:45 AM MST12:45 PM CST1:45 PM EST14:45 ET13:45 15:45 BRT14:45 1:45 PM CT | Aldosivi | Estadio Jose Amalfitani | W 3-2 |
| Fri. 24 | 3:00 PM PT4:00 PM MT5:00 PM CT6:00 PM ET22:00 GMT23:00 22:00 10:00 PM 0:00 KSA9:00 AM AET3:30 (+1) IST5:30 PM VEN2:00 (+1) UAE6:00 AM SST6:00 5:00 3:00 PM MST4:00 PM CST5:00 PM EST18:00 ET17:00 19:00 BRT18:00 5:00 PM CT | Sarmiento | Estadio Eva Peron de Junin | W 1-0 |
| October 2021 |
| Date | Time | Opponent | Venue | Result |
| Sat. 2 | 4:15 PM PT5:15 PM MT6:15 PM CT7:15 PM ET23:15 GMT0:15 23:15 11:15 PM 1:15 KSA10:15 AM AET4:45 (+1) IST6:45 PM VEN3:15 (+1) UAE7:15 AM SST7:15 6:15 4:15 PM MST5:15 PM CST6:15 PM EST19:15 ET18:15 20:15 BRT19:15 6:15 PM CT | Independiente | Estadio Jose Amalfitani | D 3-3 |
| Fri. 8 | 5:15 PM PT6:15 PM MT7:15 PM CT8:15 PM ET0:15 (+1) GMT1:15 0:15 12:15 AM 2:15 KSA11:15 AM AET5:45 (+1) IST7:45 PM VEN4:15 (+1) UAE8:15 AM SST8:15 7:15 5:15 PM MST6:15 PM CST7:15 PM EST20:15 ET19:15 21:15 BRT20:15 7:15 PM CT | Newell's Old Boys | Estadio Marcelo Alberto Bielsa | W 2-1 |
| Fri. 15 | 5:15 PM PT6:15 PM MT7:15 PM CT8:15 PM ET0:15 (+1) GMT1:15 0:15 12:15 AM 2:15 KSA11:15 AM AET5:45 (+1) IST7:45 PM VEN4:15 (+1) UAE8:15 AM SST8:15 7:15 5:15 PM MST6:15 PM CST7:15 PM EST20:15 ET19:15 21:15 BRT20:15 7:15 PM CT | Arsenal | Estadio Jose Amalfitani | D 0-0 |
| Tue. 19 | 5:15 PM PT6:15 PM MT7:15 PM CT8:15 PM ET0:15 (+1) GMT1:15 0:15 12:15 AM 2:15 KSA11:15 AM AET5:45 (+1) IST7:45 PM VEN4:15 (+1) UAE8:15 AM SST8:15 7:15 5:15 PM MST6:15 PM CST7:15 PM EST20:15 ET19:15 21:15 BRT20:15 7:15 PM CT | Central Cordoba | Estadio Alfredo Terrera | |
| Sun. 24 | 4:15 PM PT5:15 PM MT6:15 PM CT7:15 PM ET23:15 GMT0:15 23:15 11:15 PM 1:15 KSA10:15 AM AET4:45 (+1) IST6:45 PM VEN3:15 (+1) UAE7:15 AM SST7:15 6:15 4:15 PM MST5:15 PM CST6:15 PM EST19:15 ET18:15 20:15 BRT19:15 6:15 PM CT | Boca Juniors | Estadio Jose Amalfitani | |
| Sat. 30 | 2:00 PM PT3:00 PM MT4:00 PM CT5:00 PM ET21:00 GMT22:00 21:00 9:00 PM 23:00 KSA8:00 AM AET2:30 (+1) IST4:30 PM VEN1:00 (+1) UAE5:00 AM SST5:00 4:00 2:00 PM MST3:00 PM CST4:00 PM EST17:00 ET16:00 18:00 BRT17:00 4:00 PM CT | Banfield | Estadio Florencio Sola | |
| November 2021 |
| Date | Time | Opponent | Venue | Result |
| Sun. 7 | 1:00 PM PT2:00 PM MT3:00 PM CT4:00 PM ET21:00 GMT22:00 21:00 9:00 PM 23:00 KSA8:00 AM AET2:30 (+1) IST4:30 PM VEN1:00 (+1) UAE5:00 AM SST5:00 4:00 2:00 PM MST3:00 PM CST4:00 PM EST16:00 ET16:00 18:00 BRT17:00 2:00 PM CT | San Lorenzo | Estadio Jose Amalfitani | |
| Sun. 21 | TBA | Talleres de Cordoba | Estadio Francisco Cabases | |
| Wed. 24 | TBA | Argentinos Jrs. | Estadio Jose Amalfitani | |
| Sun. 28 | TBA | Estudiantes | Estadio Jorge Luis Hirschi | |
| December 2021 |
| Date | Time | Opponent | Venue | Result |
| Sun. 5 | TBA | Patronato | Estadio Jose Amalfitani | |
| Sun. 12 | TBA | Platense | Estadio Ciudad de Vicente Lopez | |
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