| July 2021 |
| Date | Time | Opponent | Venue | Result |
| Sat. 17 | 11:45 AM PT12:45 PM MT1:45 PM CT2:45 PM ET18:45 GMT19:45 18:45 6:45 PM 20:45 KSA5:45 AM AET0:15 (+1) IST2:15 PM VEN22:45 UAE2:45 AM SST2:45 1:45 11:45 AM MST12:45 PM CST1:45 PM EST14:45 ET13:45 15:45 BRT14:45 1:45 PM CT | Newell's Old Boys | Estadio Marcelo Alberto Bielsa | L 2-3 |
| Mon. 26 | 2:00 PM PT3:00 PM MT4:00 PM CT5:00 PM ET21:00 GMT22:00 21:00 9:00 PM 23:00 KSA8:00 AM AET2:30 (+1) IST4:30 PM VEN1:00 (+1) UAE5:00 AM SST5:00 4:00 2:00 PM MST3:00 PM CST4:00 PM EST17:00 ET16:00 18:00 BRT17:00 4:00 PM CT | Arsenal | Estadio Francisco Cabases | W 2-0 |
| Thu. 29 | 10:15 AM PT11:15 AM MT12:15 PM CT1:15 PM ET17:15 GMT18:15 17:15 5:15 PM 19:15 KSA4:15 AM AET22:45 IST12:45 PM VEN21:15 UAE1:15 AM SST1:15 0:15 10:15 AM MST11:15 AM CST12:15 PM EST13:15 ET12:15 14:15 BRT13:15 12:15 PM CT | Central Cordoba | Estadio Unico Madre de Ciudades | L 1-2 |
| August 2021 |
| Date | Time | Opponent | Venue | Result |
| Sun. 1 | 11:45 AM PT12:45 PM MT1:45 PM CT2:45 PM ET18:45 GMT19:45 18:45 6:45 PM 20:45 KSA5:45 AM AET0:15 (+1) IST2:15 PM VEN22:45 UAE2:45 AM SST2:45 1:45 11:45 AM MST12:45 PM CST1:45 PM EST14:45 ET13:45 15:45 BRT14:45 1:45 PM CT | Boca Juniors | Estadio Francisco Cabases | D 0-0 |
| Sat. 7 | 9:30 AM PT10:30 AM MT11:30 AM CT12:30 PM ET16:30 GMT17:30 16:30 4:30 PM 18:30 KSA3:30 AM AET22:00 IST12:00 PM VEN20:30 UAE12:30 AM SST0:30 23:30 9:30 AM MST10:30 AM CST11:30 AM EST12:30 ET11:30 13:30 BRT12:30 11:30 AM CT | Banfield | Estadio Florencio Sola | W 1-0 |
| Mon. 16 | 2:00 PM PT3:00 PM MT4:00 PM CT5:00 PM ET21:00 GMT22:00 21:00 9:00 PM 23:00 KSA8:00 AM AET2:30 (+1) IST4:30 PM VEN1:00 (+1) UAE5:00 AM SST5:00 4:00 2:00 PM MST3:00 PM CST4:00 PM EST17:00 ET16:00 18:00 BRT17:00 4:00 PM CT | San Lorenzo | Estadio Mario Alberto Kempes | W 2-0 |
| Sun. 22 | 9:30 AM PT10:30 AM MT11:30 AM CT12:30 PM ET16:30 GMT17:30 16:30 4:30 PM 18:30 KSA3:30 AM AET22:00 IST12:00 PM VEN20:30 UAE12:30 AM SST0:30 23:30 9:30 AM MST10:30 AM CST11:30 AM EST12:30 ET11:30 13:30 BRT12:30 11:30 AM CT | Union Santa Fe | Estadio 15 de Abril | W 2-1 |
| Thu. 26 | 12:30 PM PT1:30 PM MT2:30 PM CT3:30 PM ET19:30 GMT20:30 19:30 7:30 PM 21:30 KSA6:30 AM AET1:00 (+1) IST3:00 PM VEN23:30 UAE3:30 AM SST3:30 2:30 12:30 PM MST1:30 PM CST2:30 PM EST15:30 ET14:30 16:30 BRT15:30 2:30 PM CT | Argentinos Jrs. | Estadio Diego Armando Maradona | W 2-1 |
| Mon. 30 | 5:15 PM PT6:15 PM MT7:15 PM CT8:15 PM ET0:15 (+1) GMT1:15 0:15 12:15 AM 2:15 KSA11:15 AM AET5:45 (+1) IST7:45 PM VEN4:15 (+1) UAE8:15 AM SST8:15 7:15 5:15 PM MST6:15 PM CST7:15 PM EST20:15 ET19:15 21:15 BRT20:15 7:15 PM CT | Estudiantes | Estadio Francisco Cabases | W 2-0 |
| September 2021 |
| Date | Time | Opponent | Venue | Result |
| Sun. 5 | 9:30 AM PT10:30 AM MT11:30 AM CT12:30 PM ET16:30 GMT17:30 16:30 4:30 PM 18:30 KSA3:30 AM AET22:00 IST12:00 PM VEN20:30 UAE12:30 AM SST0:30 23:30 9:30 AM MST10:30 AM CST11:30 AM EST12:30 ET11:30 13:30 BRT12:30 11:30 AM CT | Patronato | Estadio Presbitero Bartolome Grella | D 0-0 |
| Tue. 14 | 10:15 AM PT11:15 AM MT12:15 PM CT1:15 PM ET17:15 GMT18:15 17:15 5:15 PM 19:15 KSA4:15 AM AET22:45 IST12:45 PM VEN21:15 UAE1:15 AM SST1:15 0:15 10:15 AM MST11:15 AM CST12:15 PM EST13:15 ET12:15 14:15 BRT13:15 12:15 PM CT | Platense | Estadio Mario Alberto Kempes | W 2-1 |
| Sat. 18 | 2:00 PM PT3:00 PM MT4:00 PM CT5:00 PM ET21:00 GMT22:00 21:00 9:00 PM 23:00 KSA8:00 AM AET2:30 (+1) IST4:30 PM VEN1:00 (+1) UAE5:00 AM SST5:00 4:00 2:00 PM MST3:00 PM CST4:00 PM EST17:00 ET16:00 18:00 BRT17:00 4:00 PM CT | Racing Club | Estadio Presidente Juan Domingo Peron | W 2-1 |
| Sat. 25 | 11:45 AM PT12:45 PM MT1:45 PM CT2:45 PM ET18:45 GMT19:45 18:45 6:45 PM 20:45 KSA5:45 AM AET0:15 (+1) IST2:15 PM VEN22:45 UAE2:45 AM SST2:45 1:45 11:45 AM MST12:45 PM CST1:45 PM EST14:45 ET13:45 15:45 BRT14:45 1:45 PM CT | Rosario Central | Estadio Francisco Cabases | W 4-1 |
| October 2021 |
| Date | Time | Opponent | Venue | Result |
| Mon. 4 | 2:00 PM PT3:00 PM MT4:00 PM CT5:00 PM ET21:00 GMT22:00 21:00 9:00 PM 23:00 KSA8:00 AM AET2:30 (+1) IST4:30 PM VEN1:00 (+1) UAE5:00 AM SST5:00 4:00 2:00 PM MST3:00 PM CST4:00 PM EST17:00 ET16:00 18:00 BRT17:00 4:00 PM CT | Defensa y Justicia | Estadio Norberto Tito Tomaghello | L 0-3 |
| Mon. 11 | 5:15 PM PT6:15 PM MT7:15 PM CT8:15 PM ET0:15 (+1) GMT1:15 0:15 12:15 AM 2:15 KSA11:15 AM AET5:45 (+1) IST7:45 PM VEN4:15 (+1) UAE8:15 AM SST8:15 7:15 5:15 PM MST6:15 PM CST7:15 PM EST20:15 ET19:15 21:15 BRT20:15 7:15 PM CT | Atlético Tucumán | Estadio Francisco Cabases | W 2-0 |
| Sun. 17 | 11:45 AM PT12:45 PM MT1:45 PM CT2:45 PM ET18:45 GMT19:45 18:45 6:45 PM 20:45 KSA5:45 AM AET0:15 (+1) IST2:15 PM VEN22:45 UAE2:45 AM SST2:45 1:45 11:45 AM MST12:45 PM CST1:45 PM EST14:45 ET13:45 15:45 BRT14:45 1:45 PM CT | Colón | Estadio Brigadier General Estanislao Lopez | L 0-1 |
| Thu. 21 | 5:15 PM PT6:15 PM MT7:15 PM CT8:15 PM ET0:15 (+1) GMT1:15 0:15 12:15 AM 2:15 KSA11:15 AM AET5:45 (+1) IST7:45 PM VEN4:15 (+1) UAE8:15 AM SST8:15 7:15 5:15 PM MST6:15 PM CST7:15 PM EST20:15 ET19:15 21:15 BRT20:15 7:15 PM CT | River Plate | Estadio Francisco Cabases | L 0-2 |
| Mon. 25 | 12:45 PM PT1:45 PM MT2:45 PM CT3:45 PM ET19:45 GMT20:45 19:45 7:45 PM 21:45 KSA6:45 AM AET1:15 (+1) IST3:15 PM VEN23:45 UAE3:45 AM SST3:45 2:45 12:45 PM MST1:45 PM CST2:45 PM EST15:45 ET14:45 16:45 BRT15:45 2:45 PM CT | Lanús | Estadio Ciudad de Lanus - Nestor Diaz Perez | |
| Sat. 30 | 2:00 PM PT3:00 PM MT4:00 PM CT5:00 PM ET21:00 GMT22:00 21:00 9:00 PM 23:00 KSA8:00 AM AET2:30 (+1) IST4:30 PM VEN1:00 (+1) UAE5:00 AM SST5:00 4:00 2:00 PM MST3:00 PM CST4:00 PM EST17:00 ET16:00 18:00 BRT17:00 4:00 PM CT | Huracán | Estadio Francisco Cabases | |
| November 2021 |
| Date | Time | Opponent | Venue | Result |
| Sat. 6 | 11:45 AM PT12:45 PM MT1:45 PM CT2:45 PM ET18:45 GMT19:45 18:45 6:45 PM 20:45 KSA5:45 AM AET0:15 (+1) IST2:15 PM VEN22:45 UAE2:45 AM SST2:45 1:45 11:45 AM MST12:45 PM CST1:45 PM EST14:45 ET13:45 15:45 BRT14:45 12:45 PM CT | Godoy Cruz | Estadio Feliciano Gambarte | |
| Sun. 21 | TBA | Vélez Sarsfield | Estadio Francisco Cabases | |
| Wed. 24 | TBA | Gimnasia LP | Estadio Juan Carmelo Zerillo | |
| Sun. 28 | TBA | Aldosivi | Estadio Francisco Cabases | |
| December 2021 |
| Date | Time | Opponent | Venue | Result |
| Sun. 5 | TBA | Sarmiento | Estadio Eva Peron de Junin | |
| Sun. 12 | TBA | Independiente | Estadio Francisco Cabases | |
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